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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STK25 All Species: 4.55
Human Site: S231 Identified Species: 8.33
UniProt: O00506 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00506 NP_006365.2 426 48112 S231 L F L I P K N S P P T L E G Q
Chimpanzee Pan troglodytes XP_001162228 584 64501 S389 L F L I P K N S P P T L E G Q
Rhesus Macaque Macaca mulatta A4K2T0 487 55587 P240 I F M I P T N P P P T F R K P
Dog Lupus familis XP_848578 318 35396 F131 L H P M R V L F L I P K N S P
Cat Felis silvestris
Mouse Mus musculus Q9Z2W1 426 48157 N231 L F L I P K N N P P T L E G H
Rat Rattus norvegicus O54748 491 56103 P237 I F M I P T N P P P T F R K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513191 426 48196 N231 L F L I P K N N P P T L E G H
Chicken Gallus gallus Q5ZJK4 486 55318 P239 I F M I P T N P P P T F R K P
Frog Xenopus laevis Q6IP06 493 56486 P236 I F M I P T N P P P T F R K P
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062 P236 I F M I P T N P P P T F R K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 P252 I F M I P Q K P P P S F R E P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NB31 497 55620 P245 I F M I P T K P P P T F K K P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38692 1080 117043 K236 M Q L I I K S K P P R L E D R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.4 38.4 71.5 N.A. 98.5 38.4 N.A. 94.3 38.8 38.5 38.6 N.A. 29.7 N.A. 35.6 N.A.
Protein Similarity: 100 72.5 57 72.5 N.A. 99.7 55.1 N.A. 97.8 55.9 56.1 56.9 N.A. 42.1 N.A. 51.7 N.A.
P-Site Identity: 100 100 46.6 6.6 N.A. 86.6 46.6 N.A. 86.6 46.6 46.6 46.6 N.A. 33.3 N.A. 40 N.A.
P-Site Similarity: 100 100 60 13.3 N.A. 93.3 60 N.A. 93.3 60 60 60 N.A. 60 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 28.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 39 8 0 % E
% Phe: 0 85 0 0 0 0 0 8 0 0 0 54 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 16 % H
% Ile: 54 0 0 93 8 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 39 16 8 0 0 0 8 8 47 0 % K
% Leu: 39 0 39 0 0 0 8 0 8 0 0 39 0 0 0 % L
% Met: 8 0 54 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 70 16 0 0 0 0 8 0 0 % N
% Pro: 0 0 8 0 85 0 0 54 93 93 8 0 0 0 62 % P
% Gln: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 16 % Q
% Arg: 0 0 0 0 8 0 0 0 0 0 8 0 47 0 8 % R
% Ser: 0 0 0 0 0 0 8 16 0 0 8 0 0 8 0 % S
% Thr: 0 0 0 0 0 47 0 0 0 0 77 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _